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猪流感疫苗试验显示年幼的孩子们将需要二个剂

时间:2010-07-27 21:52    来源:    作者: 点击:
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    Younger children will need two doses of the new swine flu vaccine, but clinical trials suggest the drug is working well, health officials said Monday.

    "Immunologically this is acting like seasonal flu and we are very pleased with that," said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases. "The response in younger children is less robust, but that is not unexpected."

    A single 15 microgram dose of swine flu vaccine is enough for kids 10 and older, while children under 10 will need two doses, 21 days apart.

    Younger kids need the double dose because their immune systems are not fully mature, Fauci said.

    Officials called the trial results "encouraging" given that three quarters of healthy kids over 10 developed an immunity to the virus.

    "Overall, this is very good news for the vaccination program," Fauci said. "76 percent is not bad at all - it's quite good I think."

    One dose was about half as effective in kids nine and younger, Fauci said, but the second dose will boost their immunity substantially.

    Kids in the clinical trial reported only minor side effects that are typical of the seasonal flu vaccine, such as soreness in the arm after a shot, Fauci said

    Some 47 children have died of swine flu since it first emerged in the spring. Unlike seasonal flu, which tends to be worst among the elderly, swine flu hits kids hardest.

    The officials recommend children and adults get the seasonal flu vaccine ahead of the swine flu vaccine to prevent logistical problems with separating the doses.

    The first of swine flu vaccine will be nasal sprays, not shots, meaning many at-risk groups will have to wait for the injectable vaccine to be released in late October.

    The city Department of Health, which will offer free vaccines to all school aged children this fall, says the spray and shot are equally effective among healthy people ages 2 to 49.

    康健官员们在周一说,年幼的孩子们将必要两个剂量新的猪流感疫苗,而临床试验表现这种药物正在很好地起浸染。

    "从免疫学上看,这样的举动象季节流感,并且我们对此很对劲,"美国国家过敏症和熏生病协会的主任安东尼 福奇博士说。"在年幼的孩子中的回响不太妥当,可是那并不意外。"

    对付 10 岁和 10 岁以上的孩子们,单个 15 微克剂量的猪流感疫苗就充足了,而 10 岁以下的孩子们将必要二个剂量,隔断 21 天。

    年幼的孩子们必要双倍剂量,由于他们的免疫体系没有完全成熟,福奇说。

    官员们称试验的功效"令人鼓动",已知四分之三 10 岁以上的康健孩子对这种病毒产生了免疫力。

    "总的来说,这对疫苗接种打算来说长短常好的动静,"福奇说。"76% 一点也不差--我感受它很不错。"

    一个剂量约莫是九岁和九岁以下孩子们的有效剂量的一半,福奇说,可是第二剂量会光鲜较着地增强他们的免疫力。

    临床试验的孩子们只呈报有稍微的副浸染,是季节性流感疫苗的规范特性,譬喻打针后的手臂酸痛,福奇说

    自从猪流感在春天初度呈现以来,约莫 47 名儿童作古于猪流感。不像季节性流感,每每是稍年尊长情形最差,猪流感冲击孩子最主要。

    官员们举荐的儿童和成人在猪流感疫苗之前接种季节性流感疫苗,采纳分隔的剂量灌注贯注后勤提供题目。

    第一剂猪流感疫苗将是鼻腔喷雾剂而不打针,意味着良多处于危害的群组将不得不守候 10 月下旬发放的打针疫苗。

    都市卫生部门--他们今年秋日将对悉数黉舍春秋的孩子们供应免费疫苗--说,在春秋 2 至 49 岁的康健人中,喷雾和打针是同样有效的。




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